Title: Activation State of the Hyperpolarization-activated Current (i H ) Modulates Temperature-sensitivity of Firing in Locus Coeruleus Neurons from Bullfrogs

نویسندگان

  • Joseph M. Santin
  • Lynn K. Hartzler
چکیده

Title: Activation state of the hyperpolarization-activated current (Ih) modulates temperature-sensitivity of firing in locus coeruleus neurons from bullfrogs Author Names: Joseph M. Santin & Lynn K. Hartzler Author Contributions: J.S. & L.H. conception and design of research; J.S. performed experiments; J.S. analyzed data; J.S. & L.H. interpreted results; J.S. wrote the manuscript; J.S. & L.K. revised, edited, and approved the final version of the manuscript. Affiliation of Authors: Department of Biological Sciences, Wright State University, 3640 Colonel Glenn Hwy, Dayton, OH 45435 Running Head: Ih activation modulates temperature-sensitivity Corresponding author: Joseph M. Santin; Address of corresponding authorDepartment of Biological Sciences, Wright State University, 3640 Colonel Glenn Hwy, Dayton, OH 45435. E-mail address of corresponding [email protected]

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Activation state of the hyperpolarization-activated current modulates temperature-sensitivity of firing in locus coeruleus neurons from bullfrogs.

Locus coeruleus neurons of anuran amphibians contribute to breathing control and have spontaneous firing frequencies that, paradoxically, increase with cooling. We previously showed that cooling inhibits a depolarizing membrane current, the hyperpolarization-activated current (I h) in locus coeruleus neurons from bullfrogs, Lithobates catesbeianus (Santin JM, Watters KC, Putnam RW, Hartzler LK....

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تاریخ انتشار 2015